rest and relax...most def...is the same as anul sex.....if u dont relax there is no way of getting in...and if u do...u risk damaging the delicate lining of the rectum and colon passage.

lubrication is a must.....again see reasons why above ^

hygene is a big issue as well....u dont want to get a nasty infection that can cause massive distress.
clean the plugs the same as u do ur vibes after using them

cg